Evaluation of the Robustness Verification of Downstream Production Process for Inactivated SARS-CoV-2 Vaccine and Different Chromatography Medium Purification Effects

Background: Large-scale vaccine production requires downstream processing that focuses on robustness, efficiency, and cost-effectiveness. Methods: To assess the robustness of the current vaccine production process, three batches of COVID-19 Omicron BA.1 strain hydrolytic concentrated solutions were...

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Bibliographic Details
Main Authors: Jia-Hui Pang, Chang-Fu Guo, Peng-Liang Hao, Sheng-Li Meng, Jing Guo, Dou Zhang, Ya-Qi Ji, Ping-Gang Ming
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/12/1/56