One-Step Regioselective Synthesis of Benzofurans from Phenols and <i>α</i>-Haloketones

Reported here is the direct synthesis of naphthofurans and benzofurans from readily available phenols and <i>&#945;</i>-haloketones promoted by titanium tetrachloride which combines Friedel&#8722;Crafts-like alkylation and intramolecular cyclodehydration into one step. This simpl...

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Bibliographic Details
Main Authors: Bingqiao Wang, Qiu Zhang, Juan Luo, Zongjie Gan, Wengao Jiang, Qiang Tang
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/11/2187