MADE: A Computational Tool for Predicting Vaccine Effectiveness for the Influenza A(H3N2) Virus Adapted to Embryonated Eggs

MADE: A Computational Tool for Predicting Vaccine Effectiveness for the Influenza A(H3N2) Virus Adapted to Embryonated Eggs

Seasonal Influenza H3N2 virus poses a great threat to public health, but its vaccine efficacy remains suboptimal. One critical step in influenza vaccine production is the viral passage in embryonated eggs. Recently, the strength of egg passage adaptation was found to be rapidly increasing with time...

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Bibliographic Details
Main Authors: Hui Chen, Junqiu Wang, Yunsong Liu, Ivy Quek Ee Ling, Chih Chuan Shih, Dafei Wu, Zhiyan Fu, Raphael Tze Chuen Lee, Miao Xu, Vincent T. Chow, Sebastian Maurer-Stroh, Da Zhou, Jianjun Liu, Weiwei Zhai
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Vaccines
Subjects:
egg passage adaptation
vaccine effectiveness
influenza H3N2 virus
adaptive evolution
vaccine production
Online Access:https://www.mdpi.com/2076-393X/10/6/907

Internet

https://www.mdpi.com/2076-393X/10/6/907

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