Transient High-Glucose Stimulation Induces Persistent Inflammatory Factor Secretion from Rat Glomerular Mesangial Cells via an Epigenetic Mechanism

Transient High-Glucose Stimulation Induces Persistent Inflammatory Factor Secretion from Rat Glomerular Mesangial Cells via an Epigenetic Mechanism

Background/Aims: Diabetic nephropathy is the one of the most serious microvascular complications of diabetes mellitus, and “metabolic memory” plays a vital role in the development of diabetic complications. To investigate the effect of epigenetics on metabolic memory, we analyzed the impact of trans...

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Bibliographic Details
Main Authors: Deng Yunlei, Fan  Qiuling, Wang Xu, Zhao Qianwen, Cao Xu, Xu Li, Wang Lining
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Diabetic Nephropathy
Histone Methylation
Metabolic Memory
Inflammatory Factors
Epigenetics
Online Access:https://www.karger.com/Article/FullText/493619

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https://www.karger.com/Article/FullText/493619

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