Necroptosis of nucleus pulposus cells involved in intervertebral disc degeneration through MyD88 signaling

Necroptosis of nucleus pulposus cells involved in intervertebral disc degeneration through MyD88 signaling

Background contextLow back pain, affecting nearly 40% of adults, mainly results from intervertebral disc degeneration (IVDD), while the pathogenesis of IVDD is still not fully elucidated. Recently, some researches have revealed that necroptosis, a programmed necrosis, participated in the progression...

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Bibliographic Details
Main Authors: Hong Fan, Zhe Chen, Hai-Bin Tang, Le-Qun Shan, Zi-Yi Chen, Shi-Chang Liu, Yong-Yuan Zhang, Xin-Yu Guo, Hao Yang, Ding-Jun Hao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Endocrinology
Subjects:
ivdd
necroptosis
nucleus pulposus cells
MyD88 signaling
low back pain
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.994307/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.994307/full

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