Exercise effects on DNA methylation in EVL, CDKN2A (p14, ARF), and ESR1 in colon tissue from healthy men and women

Exercise effects on DNA methylation in EVL, CDKN2A (p14, ARF), and ESR1 in colon tissue from healthy men and women

Physical activity reduces risk of colon cancer by 20–30%. Aberrant methylation patterns are common epigenetic alterations in colorectal adenomas, and cancers and play a role in cancer initiation and progression. Alterations identified in normal colon tissue represent apotential ‘field cancerization’...

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Bibliographic Details
Main Authors: Catherine Duggan, Ming Yu, Amber R. Willbanks, Jean de Dieu Tapsoba, Ching-Yun Wang, William M. Grady, Anne McTiernan
Format: Article
Language:English
Published: Taylor & Francis Group 2022-10-01
Series:Epigenetics
Subjects:
methylation
colon cancer
droplet digital pcr
exercise
randomized controlled trial
Online Access:http://dx.doi.org/10.1080/15592294.2021.1982512

Internet

http://dx.doi.org/10.1080/15592294.2021.1982512

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