Expression Profile of SARS-CoV-2 Host Receptors in Human Pancreatic Islets Revealed Upregulation of <i>ACE2</i> in Diabetic Donors
Cellular entry of SARS-CoV-2 is thought to occur through the binding of viral spike S1 protein to <i>ACE2</i>. The entry process involves priming of the S protein by <i>TMPRSS2</i> and <i>ADAM17</i>, which collectively mediate the binding and promote ACE2 shedding...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-08-01
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| Series: | Biology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-7737/9/8/215 |