6-Thioguanine Inhibits Herpes Simplex Virus 1 Infection of Eyes

6-Thioguanine Inhibits Herpes Simplex Virus 1 Infection of Eyes

ABSTRACT Herpes simplex virus 1 (HSV-1) infects eye corneal tissues leading to herpetic stromal keratitis (HSK), which is one of the leading causes of blindness. Here in our study, we found that 6-thioguanine (6-TG), a once clinically approved medication for child acute myelogenous leukemia, inhibit...

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Bibliographic Details
Main Authors: Deyan Chen, Ye Liu, Fang Zhang, Qiao You, Wenyuan Ma, Jing Wu, Zhiwei Wu
Format: Article
Language:English
Published: American Society for Microbiology 2021-12-01
Series:Microbiology Spectrum
Subjects:
Rac1
6-thioguanine
HSK
HSV-1
Online Access:https://journals.asm.org/doi/10.1128/Spectrum.00646-21

Internet

https://journals.asm.org/doi/10.1128/Spectrum.00646-21

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