Development and Clinical Validation of a Blood Test for Early Detection of Colorectal Adenomas and Cancer for Screening and Postpolypectomy Surveillance

Development and Clinical Validation of a Blood Test for Early Detection of Colorectal Adenomas and Cancer for Screening and Postpolypectomy Surveillance

Background and Aims: There is a lack of convenient, sensitive, noninvasive strategies for screening and surveillance for colorectal neoplasia. An assay combining the results of circulating epithelial cells (CECs) and somatic mutations of cell-free DNA adjusting for age/sex using a unique algorithm i...

Full description

Bibliographic Details
Main Authors: Shai Friedland, Drew Watson, Jennifer Pan, Yu Chen, Ashish Nimgaonkar, Zulfiqar Gulzar, Alexander Atkins, Pratyush Gupta, Julian Lucas, Jr-Ming Lai, Huangpin Hsieh, Stephen Su, Samir Gupta, John J. Sninsky, Rui Mei
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Gastro Hep Advances
Subjects:
Circulating Epithelial Cells
Colorectal Cancer
Adenoma
ctDNA Mutations
Online Access:http://www.sciencedirect.com/science/article/pii/S2772572321000303

Internet

http://www.sciencedirect.com/science/article/pii/S2772572321000303

Similar Items