Central Suppression of the GH/IGF Axis and Abrogation of Exercise-Related mTORC1/2 Activation in the Muscle of Phenotype-Selected Male Marathon Mice (DUhTP)

Central Suppression of the GH/IGF Axis and Abrogation of Exercise-Related mTORC1/2 Activation in the Muscle of Phenotype-Selected Male Marathon Mice (DUhTP)

The somatotropic axis is required for a number of biological processes, including growth, metabolism, and aging. Due to its central effects on growth and metabolism and with respect to its positive effects on muscle mass, regulation of the GH/IGF-system during endurance exercise is of particular int...

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Bibliographic Details
Main Authors: Julia Brenmoehl, Christina Walz, Caroline Caffier, Elli Brosig, Michael Walz, Daniela Ohde, Nares Trakooljul, Martina Langhammer, Siriluck Ponsuksili, Klaus Wimmers, Uwe K. Zettl, Andreas Hoeflich
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
endurance exercise
energy metabolism
pituitary gland
muscle
growth hormone
insulin-like growth factor
Online Access:https://www.mdpi.com/2073-4409/10/12/3418

Internet

https://www.mdpi.com/2073-4409/10/12/3418

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