Type I Interferon Promotes Antitumor T Cell Response in CRPC by Regulating MDSC

Background: Metastatic castration-resistant prostate cancer (CRPC) is the leading cause of death among prostate cancer patients. Here, our aim was to ascertain the immune regulatory mechanisms involved in CRPC development and identify potential immunotherapies against CRPC. Methods: A CRPC model was...

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Bibliographic Details
Main Authors: Lilv Fan, Guiliang Xu, Jingjing Cao, Min Li, Huihui Zhang, Fanlin Li, Xinyue Qi, Xiaoqing Zhang, Zeyu Li, Ping Han, Xuanming Yang
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/21/5574