Pyroptosis burden is associated with anti-TNF treatment outcome in inflammatory bowel disease: new insights from bioinformatics analysis

Abstract Biological agents known as anti-tumor necrosis factor (TNF) drugs are frequently utilized in the treatment of inflammatory bowel disease (IBD). In this study, we analyzed the shared processes of pyroptosis in Ulcerative colitis (UC) and Crohn's disease (CD), as well as explored the cor...

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Bibliographic Details
Main Authors: Xin Gao, Chen Wang, Xiao-Tong Shen, Chen-Yang Li, Yan-Chen Li, He Gao, Jia-Ming Qian, Xiao-Lan Zhang
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-43091-0