Epigenetic Mediation of <i>AKT1</i> rs1130233’s Effect on Delta-9-Tetrahydrocannabinol-Induced Medial Temporal Function during Fear Processing

High doses of delta-9-tetrahydrocannabinol (THC), the main psychoactive component of cannabis, have been shown to have anxiogenic effects. Additionally, THC effects have been shown to be modulated by genotype, including the single nucleotide polymorphism (SNP) rs1130233 at the protein kinase <i&g...

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Detalles Bibliográficos
Main Authors: Grace Blest-Hopley, Marco Colizzi, Diana Prata, Vincent Giampietro, Michael Brammer, Philip McGuire, Sagnik Bhattacharyya
Formato: Artigo
Idioma:English
Publicado: MDPI AG 2021-09-01
Series:Brain Sciences
Subjects:
Acceso en liña:https://www.mdpi.com/2076-3425/11/9/1240