The evolution of humoral immune responses to past and novel influenza virus strains gives evidence for antigenic seniority

The high genetic and antigenic variability of influenza virus and the repeated exposures of individuals to the virus over time account for the human immune responses toward this pathogen to continuously evolve during the lifespan of an individual. Influenza-specific immune memory to past strains has...

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Bibliographic Details
Main Authors: Federica Sicca, Eleni Sakorafa, Anouk de Jonge, Jacqueline de Vries-Idema, Fan Zhou, Rebecca Jane Cox, Anke Huckriede
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.987984/full