IL-33/ST2 axis is involved in disease progression in the spleen during Leishmania donovani infection

Abstract Background During infection with Leishmania donovani, parasite control is linked to the systemic Th1 immune response, but in infected organs (liver, spleen and bone marrow), the response differs according to the micro-environment. The pleiomorphic cytokine interleukin-33 (IL-33) exerts vari...

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Bibliographic Details
Main Authors: Aurore Lamberet, Octavie Rostan, Sarah Dion, Aurélien Jan, Hélène Guegan, Christelle Manuel, Michel Samson, Jean-Pierre Gangneux, Florence Robert-Gangneux
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Parasites & Vectors
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13071-020-04190-3