The Arg/N-Degron Pathway—A Potential Running Back in Fine-Tuning the Inflammatory Response?

Recognition of danger signals by a cell initiates a powerful cascade of events generally leading to inflammation. Inflammatory caspases and several other proteases become activated and subsequently cleave their target proinflammatory mediators. The irreversible nature of this process implies that th...

Full description

Bibliographic Details
Main Authors: Dominique Leboeuf, Maxim Pyatkov, Timofei S. Zatsepin, Konstantin Piatkov
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/6/903