Protein restriction during lactation causes transgenerational metabolic dysfunction in adult rat offspring

Protein restriction during lactation causes transgenerational metabolic dysfunction in adult rat offspring

IntroductionProtein restriction during lactation can induce metabolic dysfunctions and has a huge impact on the offspring’s phenotype later in its life. We tested whether the effects of a maternal low-protein diet (LP) in rats can be transmitted to the F2 generation and increase their vulnerability...

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Bibliographic Details
Main Authors: Rodrigo Vargas, Isabela Peixoto Martins, Camila Cristina Ianoni Matiusso, Raiana Aparecida Casagrande, Camila Benan Zara, Anna Carolina Huppes de Souza, William Pereira Horst, Taina Cristine Sieklicki, Tania Cristina Alexandrino Becker, Naiara Cristina Lucredi, Jurandir Fernando Comar, Ananda Malta, Paulo Cezar de Freitas Mathias
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Nutrition
Subjects:
metabolic programming
maternal malnutrition
steatosis
thrifty phenotype hypothesis
metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.1062116/full

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https://www.frontiersin.org/articles/10.3389/fnut.2022.1062116/full

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