Undifferentiated and differentiated PC12 cells protected by huprines against injury induced by hydrogen peroxide.

Oxidative stress is implicated in the pathogenesis of neurodegenerative disorders and hydrogen peroxide (H2O2) plays a central role in the stress. Huprines, a group of potent acetylcholinesterase inhibitors (AChEIs), have shown a broad cholinergic pharmacological profile. Recently, it has been obser...

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Bibliographic Details
Main Authors: Marta Pera, Pelayo Camps, Diego Muñoz-Torrero, Belen Perez, Albert Badia, M Victoria Clos Guillen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3781080?pdf=render