The HLA class II Allele DRB1*1501 is over-represented in patients with idiopathic pulmonary fibrosis.

The HLA class II Allele DRB1*1501 is over-represented in patients with idiopathic pulmonary fibrosis.

Idiopathic pulmonary fibrosis (IPF) is a progressive and medically refractory lung disease with a grim prognosis. Although the etiology of IPF remains perplexing, abnormal adaptive immune responses are evident in many afflicted patients. We hypothesized that perturbations of human leukocyte antigen...

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Detalhes bibliográficos
Principais autores: Jianmin Xue, Bernadette R Gochuico, Ahmad Samer Alawad, Carol A Feghali-Bostwick, Imre Noth, Steven D Nathan, Glenn D Rosen, Ivan O Rosas, Sanja Dacic, Iclal Ocak, Carl R Fuhrman, Karen T Cuenco, Mary A Smith, Susan S Jacobs, Adriana Zeevi, Penelope A Morel, Joseph M Pilewski, Vincent G Valentine, Kevin F Gibson, Naftali Kaminski, Frank C Sciurba, Yingze Zhang, Steven R Duncan
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2011-02-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3044131?pdf=render

Internet

http://europepmc.org/articles/PMC3044131?pdf=render

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