Non-hypertrophic chondrogenesis of mesenchymal stem cells through mechano-hypoxia programing

Cartilage tissue engineering aims to generate functional replacements to treat cartilage defects from damage and osteoarthritis. Human bone marrow-derived mesenchymal stem cells (hBM-MSC) are a promising cell source for making cartilage, but current differentiation protocols require the supplementat...

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Bibliographic Details
Main Authors: David Xinzheyang Li, Zhiyao Ma, Alexander RA Szojka, Xiaoyi Lan, Melanie Kunze, Aillette Mulet-Sierra, Lindsey Westover, Adetola B Adesida
Format: Article
Language:English
Published: SAGE Publishing 2023-05-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314231172574