New idea to promote the clinical applications of stem cells or their extracellular vesicles in central nervous system disorders: Combining with intranasal delivery

The clinical translation of stem cells and their extracellular vesicles (EVs)-based therapy for central nervous system (CNS) diseases is booming. Nevertheless, the insufficient CNS delivery and retention together with the invasiveness of current administration routes prevent stem cells or EVs from f...

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Bibliographic Details
Main Authors: Yaosheng Li, Honghui Wu, Xinchi Jiang, Yunfei Dong, Juanjuan Zheng, Jianqing Gao
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383522001587