An accelerated Rauhut–Currier dimerization enabled the synthesis of (±)-incarvilleatone and anticancer studies

An accelerated Rauhut–Currier dimerization enabled the synthesis of (±)-incarvilleatone and anticancer studies

The total synthesis of racemic incarvilleatone has been achieved by utilizing unexplored accelerated Rauhut–Currier (RC) dimerization. The other key steps of the synthesis are oxa-Michael and aldol reactions in a tandem sequence. Racemic incarvilleatone was separated by chiral HPLC and the configura...

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Bibliographic Details
Main Authors: Tharun K. Kotammagari, Sweta Misra, Sayantan Paul, Sunita Kunte, Rajesh G. Gonnade, Manas K. Santra, Asish K. Bhattacharya
Format: Article
Language:English
Published: Beilstein-Institut 2023-02-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
dimerization
incarviditone
incarvilleatone
oxa-michael
rauhut–currier
Online Access:https://doi.org/10.3762/bjoc.19.19

Internet

https://doi.org/10.3762/bjoc.19.19

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