Co-inhibition of BCL-XL and MCL-1 with selective BCL-2 family inhibitors enhances cytotoxicity of cervical cancer cell lines

Development of resistance to chemo- and radiotherapy in patients suffering from advanced cervical cancer narrows the therapeutic window for conventional therapies. Previously we reported that a combination of the selective BCL-2 family inhibitors ABT-263 and A-1210477 decreased cell proliferation in...

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Bibliographic Details
Main Authors: Siti Fairus Abdul Rahman, Kalaivani Muniandy, Yong Kit Soo, Elvin Yu Huai Tiew, Ke Xin Tan, Timothy E. Bates, Nethia Mohana-Kumaran
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580820300650