LncRNA NEAT1 promotes proliferation, migration, invasion and epithelial-mesenchymal transition process in TGF-β2-stimulated lens epithelial cells through regulating the miR-486-5p/SMAD4 axis

LncRNA NEAT1 promotes proliferation, migration, invasion and epithelial-mesenchymal transition process in TGF-β2-stimulated lens epithelial cells through regulating the miR-486-5p/SMAD4 axis

Abstract Background Abnormal proliferation, metastasis and epithelial-mesenchymal transformation (EMT) of lens epithelial cells (LECs) are direct factors of posterior capsular opacification (PCO). Nuclear enriched abundant transcript 1 (NEAT1) has been shown to promote cell proliferation, metastasis...

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Bibliographic Details
Main Authors: Huajun Wang, Guangying Zheng
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Cancer Cell International
Subjects:
Posterior capsular opacification
TGF-β2
NEAT1
miR-486-5p
SMAD4
Online Access:http://link.springer.com/article/10.1186/s12935-020-01619-8

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http://link.springer.com/article/10.1186/s12935-020-01619-8

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