Regulation of the Aurora-A gene following topoisomerase I inhibition: implication of the Myc transcription Factor
<p>Abstract</p> <p>During the G2 phase of the cell cycle, the Aurora-A kinase plays an important role in centrosome maturation and progression to mitosis. In this study, we show in colorectal cell lines that Aurora-A expression is downregulated in response to topoisomerase I inhibi...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-08-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/9/1/205 |