Regulation of the Aurora-A gene following topoisomerase I inhibition: implication of the Myc transcription Factor

Regulation of the Aurora-A gene following topoisomerase I inhibition: implication of the Myc transcription Factor

<p>Abstract</p> <p>During the G2 phase of the cell cycle, the Aurora-A kinase plays an important role in centrosome maturation and progression to mitosis. In this study, we show in colorectal cell lines that Aurora-A expression is downregulated in response to topoisomerase I inhibi...

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Bibliographic Details
Main Authors: Valo Isabelle, Giraud Sandrine, Troadec Marie-Bérangère, Vigneron Arnaud, Cherier Julia, Courapied Sandy, Prigent Claude, Gamelin Erick, Coqueret Olivier, Barré Benjamin
Format: Article
Language:English
Published: BMC 2010-08-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/205

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http://www.molecular-cancer.com/content/9/1/205

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