Integrative Analysis Constructs an Extracellular Matrix-Associated Gene Signature for the Prediction of Survival and Tumor Immunity in Lung Adenocarcinoma

Integrative Analysis Constructs an Extracellular Matrix-Associated Gene Signature for the Prediction of Survival and Tumor Immunity in Lung Adenocarcinoma

Background: Lung adenocarcinoma (LUAD) accounts for the majority of lung cancers, and the survival of patients with advanced LUAD is poor. The extracellular matrix (ECM) is a fundamental component of the tumor microenvironment (TME) that determines the oncogenesis and antitumor immunity of solid tum...

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Bibliographic Details
Main Authors: Lingyan Xiao, Qian Li, Yongbiao Huang, Zhijie Fan, Wan Qin, Bo Liu, Xianglin Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
lung adenocarcinoma
extracellar matrix
prognostic signature
tumor micoenvironment
immunotharapy
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.835043/full

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https://www.frontiersin.org/articles/10.3389/fcell.2022.835043/full

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