Everolimus in the management of metastatic neuroendocrine tumours
Neuroendocrine tumours are increasing in incidence and cause a variety of symptoms. The mammalian target of rapamycin (mTOR) pathway plays a key role in neuroendocrine tumour (NET) pathogenesis, leading to increased lipid synthesis, protein synthesis and cellular growth. Upregulation of this pathway...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2017-01-01
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Series: | Therapeutic Advances in Gastroenterology |
Online Access: | https://doi.org/10.1177/1756283X16674660 |