Extra-hematopoietic immunomodulatory role of the guanine-exchange factor DOCK2

Extra-hematopoietic immunomodulatory role of the guanine-exchange factor DOCK2

The guanine exchange factor DOCK2 regulates the development of immunomodulatory function in human stromal cells (mesenchymal stem/progenitor cells (MSPC) and fibroblasts), as demonstrated in three models.

Bibliographic Details
Main Authors: Cornelia Scharler, Rodolphe Poupardin, Patricia Ebner-Peking, Martin Wolf, Christina Schreck, Gabriele Brachtl, Andre Cronemberger Andrade, Linda Krisch, Laurence Daheron, Katharina Schallmoser, Karsten Jürchott, Judit Küchler, Harald Stachelscheid, Hans-Dieter Volk, Robert A. J. Oostendorp, Dirk Strunk
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-04078-1

Internet

https://doi.org/10.1038/s42003-022-04078-1

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