General Health Benefits and Pharmacological Activities of <i>Triticum aestivum</i> L.

Common wheat (<i>Triticum aestivum</i>), one of the world’s most consumed cereal grains, is known for its uses in baking and cooking in addition to its medicinal uses. As this plant’s medical benefits are enormous and scattered, this narrative review was aimed at describing the pharmacol...

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Main Authors: Said Moshawih, Rabi’atul Nur Amalia Abdullah Juperi, Ganesh Sritheran Paneerselvam, Long Chiau Ming, Kai Bin Liew, Bey Hing Goh, Yaser Mohammed Al-Worafi, Chee-Yan Choo, Shobna Thuraisingam, Hui Poh Goh, Nurolaini Kifli
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/6/1948
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author Said Moshawih
Rabi’atul Nur Amalia Abdullah Juperi
Ganesh Sritheran Paneerselvam
Long Chiau Ming
Kai Bin Liew
Bey Hing Goh
Yaser Mohammed Al-Worafi
Chee-Yan Choo
Shobna Thuraisingam
Hui Poh Goh
Nurolaini Kifli
author_facet Said Moshawih
Rabi’atul Nur Amalia Abdullah Juperi
Ganesh Sritheran Paneerselvam
Long Chiau Ming
Kai Bin Liew
Bey Hing Goh
Yaser Mohammed Al-Worafi
Chee-Yan Choo
Shobna Thuraisingam
Hui Poh Goh
Nurolaini Kifli
author_sort Said Moshawih
collection DOAJ
description Common wheat (<i>Triticum aestivum</i>), one of the world’s most consumed cereal grains, is known for its uses in baking and cooking in addition to its medicinal uses. As this plant’s medical benefits are enormous and scattered, this narrative review was aimed at describing the pharmacological activities, phytochemistry, and the nutritional values of <i>Triticum aestivum</i>. It is a good source of dietary fiber, resistant starch, phenolic acids, alkylresorcinols, lignans, and diverse antioxidant compounds such as carotenoids, tocopherols and tocotrienols. These constituents provide <i>Triticum aestivum</i> with a wide range of pharmacological properties, including anticancer, antimicrobial, antidiabetic, hypolipemic, antioxidant, laxative, and moisturizing effects. This review summarized the established benefits of wheat in human health, the mode of action, and different clinical, in vitro and in vivo studies for different varieties and cultivars. This review also gives an insight for future research into the better use of this plant as a functional food. More clinical trials, in vivo and in vitro studies are warranted to broaden the knowledge about the effect of <i>Triticum aestivum</i> on nutrition-related diseases prevention, and physical and mental well-being sustenance.
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spelling doaj.art-fd662c994ecd44a4a636dc24bf151d992023-11-30T21:43:41ZengMDPI AGMolecules1420-30492022-03-01276194810.3390/molecules27061948General Health Benefits and Pharmacological Activities of <i>Triticum aestivum</i> L.Said Moshawih0Rabi’atul Nur Amalia Abdullah Juperi1Ganesh Sritheran Paneerselvam2Long Chiau Ming3Kai Bin Liew4Bey Hing Goh5Yaser Mohammed Al-Worafi6Chee-Yan Choo7Shobna Thuraisingam8Hui Poh Goh9Nurolaini Kifli10PAP Rashidah Sa’adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Gadong BE 1410, BruneiPAP Rashidah Sa’adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Gadong BE 1410, BruneiSchool of Pharmacy, Taylor’s University, Subang Jaya 47500, MalaysiaPAP Rashidah Sa’adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Gadong BE 1410, BruneiFaculty of Pharmacy, University of Cyberjaya, Cyberjaya 63000, MalaysiaBiofunctional Molecule Exploratory Research Group (BMEX), School of Pharmacy, Monash University Malaysia, Bandar Sunway 47500, MalaysiaCollege of Medical Sciences, Azal University for Human Development, Amran P.O. Box 447, YemenFaculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam 42300, MalaysiaFaculty of Science, Universiti Putra Malaysia, Seri Kembangan 43400, MalaysiaPAP Rashidah Sa’adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Gadong BE 1410, BruneiPAP Rashidah Sa’adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Gadong BE 1410, BruneiCommon wheat (<i>Triticum aestivum</i>), one of the world’s most consumed cereal grains, is known for its uses in baking and cooking in addition to its medicinal uses. As this plant’s medical benefits are enormous and scattered, this narrative review was aimed at describing the pharmacological activities, phytochemistry, and the nutritional values of <i>Triticum aestivum</i>. It is a good source of dietary fiber, resistant starch, phenolic acids, alkylresorcinols, lignans, and diverse antioxidant compounds such as carotenoids, tocopherols and tocotrienols. These constituents provide <i>Triticum aestivum</i> with a wide range of pharmacological properties, including anticancer, antimicrobial, antidiabetic, hypolipemic, antioxidant, laxative, and moisturizing effects. This review summarized the established benefits of wheat in human health, the mode of action, and different clinical, in vitro and in vivo studies for different varieties and cultivars. This review also gives an insight for future research into the better use of this plant as a functional food. More clinical trials, in vivo and in vitro studies are warranted to broaden the knowledge about the effect of <i>Triticum aestivum</i> on nutrition-related diseases prevention, and physical and mental well-being sustenance.https://www.mdpi.com/1420-3049/27/6/1948wheat<i>Triticum aestivum</i>functional foodanticancerantimicrobialantidiabetic
spellingShingle Said Moshawih
Rabi’atul Nur Amalia Abdullah Juperi
Ganesh Sritheran Paneerselvam
Long Chiau Ming
Kai Bin Liew
Bey Hing Goh
Yaser Mohammed Al-Worafi
Chee-Yan Choo
Shobna Thuraisingam
Hui Poh Goh
Nurolaini Kifli
General Health Benefits and Pharmacological Activities of <i>Triticum aestivum</i> L.
Molecules
wheat
<i>Triticum aestivum</i>
functional food
anticancer
antimicrobial
antidiabetic
title General Health Benefits and Pharmacological Activities of <i>Triticum aestivum</i> L.
title_full General Health Benefits and Pharmacological Activities of <i>Triticum aestivum</i> L.
title_fullStr General Health Benefits and Pharmacological Activities of <i>Triticum aestivum</i> L.
title_full_unstemmed General Health Benefits and Pharmacological Activities of <i>Triticum aestivum</i> L.
title_short General Health Benefits and Pharmacological Activities of <i>Triticum aestivum</i> L.
title_sort general health benefits and pharmacological activities of i triticum aestivum i l
topic wheat
<i>Triticum aestivum</i>
functional food
anticancer
antimicrobial
antidiabetic
url https://www.mdpi.com/1420-3049/27/6/1948
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