The Evolution of Circulating Biomarkers for Use in Acetaminophen/Paracetamol-Induced Liver Injury in Humans: A Scoping Review

Acetaminophen (APAP) is a widely used drug, but overdose can cause severe acute liver injury. The first reports of APAP hepatotoxicity in humans were published in 1966, shortly after the development of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) as the first biomarkers of liv...

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Bibliographic Details
Main Authors: Mitchell R. McGill, Steven C. Curry
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Livers
Subjects:
Online Access:https://www.mdpi.com/2673-4389/3/4/39