MCL-1 Inhibitor S63845 Distinctively Affects Intramedullary and Extramedullary Hematopoiesis

MCL-1 Inhibitor S63845 Distinctively Affects Intramedullary and Extramedullary Hematopoiesis

Conventional chemotherapy for killing cancer cells using cytotoxic drugs suffers from low selectivity, significant toxicity, and a narrow therapeutic index. Hyper-specific targeted drugs achieve precise destruction of tumors by inhibiting molecular pathways that are critical to tumor growth. Myeloid...

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Bibliographic Details
Main Authors: Hexiao Zhang, Fei Li, Ming Yang, Wenshan Zhang, Mei He, Hui Xu, Chaoqun Wang, Yiran Zhang, Wei Wang, Yingdai Gao, Xue Du, Yinghui Li
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pharmaceutics
Subjects:
targeted drugs
MCL-1 inhibitor
hematopoietic suppression
extramedullary hematopoiesis
Online Access:https://www.mdpi.com/1999-4923/15/4/1085

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https://www.mdpi.com/1999-4923/15/4/1085

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