Azacarbazole n-3 and n-6 polyunsaturated fatty acids ethyl esters nanoemulsion with enhanced efficacy against Plasmodium falciparum

Azacarbazole n-3 and n-6 polyunsaturated fatty acids ethyl esters nanoemulsion with enhanced efficacy against Plasmodium falciparum

Alternative therapies are necessary for the treatment of malaria due to emerging drug resistance. However, many promising antimalarial compounds have poor water solubility and suffer from the lack of suitable delivery systems, which seriously limits their activity. To address this problem, we synthe...

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Bibliographic Details
Main Authors: Anna Jaromin, Silvia Parapini, Nicoletta Basilico, Magdalena Zaremba-Czogalla, Agnieszka Lewińska, Agnieszka Zagórska, Maria Walczak, Bożena Tyliszczak, Aleksandra Grzeszczak, Marcin Łukaszewicz, Łukasz Kaczmarek, Jerzy Gubernator
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-04-01
Series:Bioactive Materials
Subjects:
Azacarbazoles
Flax oil
n-3 and n-6 polyunsaturated fatty acids ethyl esters
Nanoemulsion
P. falciparum
Malaria
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X20302553

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http://www.sciencedirect.com/science/article/pii/S2452199X20302553

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