Signalling pathways in the osteogenic differentiation of periodontal ligament stem cells

PDLSCs possess multidirectional differentiation potential and self-renewal ability. In the inflammatory environment, signalling pathways, such as Wnt/β-catenin, Wnt/Ca2+, Wnt/PCP, NF-κB, MAPK, BMPs, and PI3K/AKT, are involved in regulating the osteogenic differentiation of PDLSCs. In addition, multi...

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Bibliographic Details
Main Authors: Ru Liuyu, Pan Bowen, Zheng Jiwei
Format: Article
Language:English
Published: De Gruyter 2023-09-01
Series:Open Life Sciences
Subjects:
Online Access:https://doi.org/10.1515/biol-2022-0706