Radiation-induced FAP + fibroblasts are involved in keloid recurrence after radiotherapy

Background: Keloid scars (KSs), which are composed of abnormal hyperplastic scar tissue, form during skin wound healing due to excessive fibroblast activation and collagen secretion. Although surgical resection and radiation therapy are used to prevent recurrence, KS recurrence rates range from 15 t...

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Bibliographic Details
Main Authors: Yan Gao, Xue Hou, Yuyin Dai, Ting Yang, Kexin Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.957363/full