MicroRNA-21a-5p inhibition alleviates systemic sclerosis by targeting STAT3 signaling

Abstract Background MicroRNA (miRNA)-21-5p participates in various biological processes, including cancer and autoimmune diseases. However, its role in the development of fibrosis in the in vivo model of systemic sclerosis (SSc) has not been reported. This study investigated the effects of miRNA-21a...

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Bibliographic Details
Main Authors: Jin-Sil Park, Chongtae Kim, JeongWon Choi, Ha Yeon Jeong, Young-Mee Moon, Hoin Kang, Eun Kyung Lee, Mi-La Cho, Sung-Hwan Park
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Translational Medicine
Online Access:https://doi.org/10.1186/s12967-024-05056-3