MicroRNA-21a-5p inhibition alleviates systemic sclerosis by targeting STAT3 signaling
Abstract Background MicroRNA (miRNA)-21-5p participates in various biological processes, including cancer and autoimmune diseases. However, its role in the development of fibrosis in the in vivo model of systemic sclerosis (SSc) has not been reported. This study investigated the effects of miRNA-21a...
Main Authors: | Jin-Sil Park, Chongtae Kim, JeongWon Choi, Ha Yeon Jeong, Young-Mee Moon, Hoin Kang, Eun Kyung Lee, Mi-La Cho, Sung-Hwan Park |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-04-01
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Series: | Journal of Translational Medicine |
Online Access: | https://doi.org/10.1186/s12967-024-05056-3 |
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