Combinatorial Metabolic Engineering in <i>Saccharomyces cerevisiae</i> for the Enhanced Production of the FPP-Derived Sesquiterpene Germacrene

Combinatorial Metabolic Engineering in <i>Saccharomyces cerevisiae</i> for the Enhanced Production of the FPP-Derived Sesquiterpene Germacrene

Farnesyl diphosphate (FPP)-derived isoprenoids represent a diverse group of plant secondary metabolites with great economic potential. To enable their efficient production in the heterologous host <i>Saccharomyces cerevisiae</i>, we refined a metabolic engineering strategy using the CRIS...

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Bibliographic Details
Main Authors: Jan Niklas Bröker, Boje Müller, Dirk Prüfer, Christian Schulze Gronover
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Bioengineering
Subjects:
yeast
metabolic engineering
CRISPR-Cas
farnesyl diphosphate
sesquiterpenes
Online Access:https://www.mdpi.com/2306-5354/7/4/135

Internet

https://www.mdpi.com/2306-5354/7/4/135

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