Evaluation of the synergistic effects of epigallocatechin-3-gallate-loaded PEGylated-PLGA nanoparticles with nimodipine against neuronal injury after subarachnoid hemorrhage

Evaluation of the synergistic effects of epigallocatechin-3-gallate-loaded PEGylated-PLGA nanoparticles with nimodipine against neuronal injury after subarachnoid hemorrhage

Subarachnoid hemorrhage (SAH) is a devastating subtype of stroke with high mortality and morbidity. Although serious side effects might occur, nimodipine, a second-generation 1,4-dihydropyridine calcium channel blocker, is clinically used to improve neurological outcomes after SAH. Recently, (-)-epi...

Full description

Bibliographic Details
Main Authors: Xianguang Yang, Mengguo Han, Xue Wang, Jian Wang, Xiaoxue Sun, Chunyan Zhang, Shuaiguo Yan, Liyong Huang, Ying Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Nutrition
Subjects:
EGCG
subarachnoid hemorrhage
PLGA-PEG
nanoparticles
nimodipine
autophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.953326/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2022.953326/full

Similar Items