Tuning apicobasal polarity and junctional recycling in the hemogenic endothelium orchestrates the morphodynamic complexity of emerging pre-hematopoietic stem cells

Hematopoietic stem cells emerge in the embryo from an aortic-derived tissue called the hemogenic endothelium (HE). The HE appears to give birth to cells of different nature and fate but the molecular principles underlying this complexity are largely unknown. Here we show, in the zebrafish embryo, th...

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Bibliografiske detaljer
Main Authors: Léa Torcq, Sara Majello, Catherine Vivier, Anne A Schmidt
Format: Article
Sprog:English
Udgivet: eLife Sciences Publications Ltd 2024-05-01
Serier:eLife
Fag:
Online adgang:https://elifesciences.org/articles/91429