An integrated pathway based on in vitro data for the human hazard assessment of nanomaterials

In line with the 3R concept, nanotoxicology is shifting from a phenomenological to a mechanistic approach based on in vitro and in silico methods, with a consequent reduction in animal testing. Risk Assessment (RA) and Life Cycle Assessment (LCA) methodologies, which traditionally rely on in vivo to...

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Bibliographic Details
Main Authors: Daina Romeo, Beatrice Salieri, Roland Hischier, Bernd Nowack, Peter Wick
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Environment International
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412019338474