Human Alpha 1 Antitrypsin Suppresses NF-κB Activity and Extends Lifespan in Adult <i>Drosophila</i>

Human Alpha 1 Antitrypsin Suppresses NF-κB Activity and Extends Lifespan in Adult <i>Drosophila</i>

Human alpha 1 antitrypsin (hAAT) is a multifunctional protein that has been shown to have anti-inflammatory and cellular protective properties. While previous studies demonstrated the antiaging potential of hAAT, the mechanism(s) underlying the antiaging effect remain elusive. In this study, we perf...

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Bibliographic Details
Main Authors: Ye Yuan, Max Van Belkum, Alana O’Brien, Alain Garcia, Karla Troncoso, Ahmed S. Elshikha, Lei Zhou, Sihong Song
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomolecules
Subjects:
human alpha-1 antitrypsin (hAAT)
senescence
NF-κB
SASP
<i>Drosophila</i>
Online Access:https://www.mdpi.com/2218-273X/12/10/1347

Internet

https://www.mdpi.com/2218-273X/12/10/1347

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