Evolution, genomic analysis, and reconstruction of isobutanol tolerance in Escherichia coli
Escherichia coli has been engineered to produce isobutanol, with titers reaching greater than the toxicity level. However, the specific effects of isobutanol on the cell have never been fully understood. Here, we aim to identify genotype–phenotype relationships in isobutanol response. An isobutanol‐...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2010-01-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.1038/msb.2010.98 |