Local production of reactive oxygen species drives vincristine-induced axon degeneration

Abstract Neurological side effects arising from chemotherapy, such as severe pain and cognitive impairment, are a major concern for cancer patients. These major side effects can lead to reduction or termination of chemotherapy medication in patients, negatively impacting their prognoses. With cancer...

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Bibliographic Details
Main Authors: Jorge Gomez-Deza, Anastasia L. Slavutsky, Matthew Nebiyou, Claire E. Le Pichon
Format: Article
Language:English
Published: Nature Publishing Group 2023-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06227-8