Characterization of an aspartate aminotransferase encoded by YPO0623 with frequent nonsense mutations in Yersinia pestis

Characterization of an aspartate aminotransferase encoded by YPO0623 with frequent nonsense mutations in Yersinia pestis

Yersinia pestis, the causative agent of plague, is a genetically monomorphic bacterial pathogen that evolved from Yersinia pseudotuberculosis approximately 7,400 years ago. We observed unusually frequent mutations in Y. pestis YPO0623, mostly resulting in protein translation termination, which impli...

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Bibliographic Details
Main Authors: Junyan Jin, Liting Xiao, Yarong Wu, Zhulin Sun, Ziyao Xiong, Yanbing Li, Yanting Zhao, Wenwu Yao, Leiming Shen, Yiming Cui, Yafang Tan, Yanping Han, Zongmin Du, Yujun Cui, Ruifu Yang, Kai Song, Yajun Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Yersinia pestis
YPO0623
aspartate aminotransferase
T6SS
genome decay
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1288371/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2023.1288371/full

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