The Evolution of Nitric Oxide Function: From Reactivity in the Prebiotic Earth to Examples of Biological Roles and Therapeutic Applications

Nitric oxide was once considered to be of marginal interest to the biological sciences and medicine; however, there is now wide recognition, but not yet a comprehensive understanding, of its functions and effects. NO is a reactive, toxic free radical with numerous biological targets, especially meta...

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Bibliographic Details
Main Authors: Mark Shepherd, Daniela Giordano, Cinzia Verde, Robert K. Poole
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/11/7/1222