APOBEC Alteration Contributes to Tumor Growth and Immune Escape in Pan-Cancer

The accumulating evidence demonstrates that the apolipoprotein B mRNA editing enzyme catalytic polypeptide-like (APOBEC), DNA-editing protein plays an important role in the molecular pathogenesis of cancer. In particular, the APOBEC3 family was shown to induce tumor mutations by an aberrant DNA edit...

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Bibliographic Details
Main Authors: Honghong Guo, Ling Zhu, Lu Huang, Zhen Sun, Hui Zhang, Baoting Nong, Yuanyan Xiong
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/12/2827