Identification of ER/SR resident proteins as biomarkers for ER/SR calcium depletion in skeletal muscle cells

Abstract Background Aberrations to endoplasmic/sarcoplasmic reticulum (ER/SR) calcium concentration can result in the departure of endogenous proteins in a phenomenon termed exodosis. Redistribution of the ER/SR proteome can have deleterious effects to cell function and cell viability, often contrib...

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Bibliographic Details
Main Authors: Lacey K. Greer, Katherine G. Meilleur, Brandon K. Harvey, Emily S. Wires
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Online Access:https://doi.org/10.1186/s13023-022-02368-9