Association between homologous recombination deficiency and outcomes with platinum and platinum-free chemotherapy in patients with triple-negative breast cancer

Association between homologous recombination deficiency and outcomes with platinum and platinum-free chemotherapy in patients with triple-negative breast cancer

Objective: The choice of chemotherapeutic regimen for triple-negative breast cancer (TNBC) remains controversial. Homologous recombination deficiency (HRD) has attracted increasing attention in informing chemotherapy treatment. This study was aimed at investigating the feasibility of HRD as a clinic...

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Bibliographic Details
Main Authors: Yimeng Chen, Xue Wang, Feng Du, Jian Yue, Yiran Si, Xiaochen Zhao, Lina Cui, Bei Zhang, Ting Bei, Binghe Xu, Peng Yuan
Format: Article
Language:English
Published: China Anti-Cancer Association 2023-02-01
Series:Cancer Biology & Medicine
Subjects:
homologous recombination deficiency
triple-negative breast cancer
platinum
survival
brca
Online Access:https://www.cancerbiomed.org/content/20/2/155

Internet

https://www.cancerbiomed.org/content/20/2/155

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