Cyclodextrins as modulators for separation of charged variants of mAbs by capillary zone electrophoresis
Charge heterogeneity is a critical quality attribute for mAb-based therapeutics. Its characterization involves the identification of charge variant species in the final formulation. Capillary zone electrophoresis (CZE) is a valuable tool to assess charge heterogeneity, but typically offers incomplet...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-11-01
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| Series: | Journal of Chromatography Open |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772391721000116 |