ATP binding cassette transporter G5 and G8 genotypes and plasma lipoprotein levels before and after treatment with atorvastatin

ATP binding cassette transporter G5 and G8 genotypes and plasma lipoprotein levels before and after treatment with atorvastatin

The mechanisms responsible for interindividual variation in response to statin therapy remain uncertain. It has been shown that hepatic cholesterol synthesis is associated with ATP binding cassette transporter G5 and G8 (ABCG5/8) activities. To test the hypothesis that genetic variation in ABCG5/8 m...

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Bibliographic Details
Main Authors: Kouji Kajinami, Margaret E. Brousseau, Chorthip Nartsupha, Jose M. Ordovas, Ernst J. Schaefer
Format: Article
Language:English
Published: Elsevier 2004-04-01
Series:Journal of Lipid Research
Subjects:
3-hydroxy-3-methylglutaryl-CoA reductase inhibitor
pharmacogenetics
low density lipoprotein cholesterol
adenosine 5′-triphosphate binding cassette transporter
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520318496

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http://www.sciencedirect.com/science/article/pii/S0022227520318496

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